Correction: Chemical approaches to synthetic polymer surface biofunctionalization for targeted cell adhesion using small binding motifs
نویسندگان
چکیده
منابع مشابه
Synthetic approaches to Small Cluster Oligosaccharide Mimetics
We have synthesized a variety of Small Cluster Oligosaccharide Mimetics (SCOM) with presumably enhanced metabolic stability. Their monosaccharidic units are linked by non-physiological C-C or C-N bonds, and/or include unphysiological or L-configurated polyhydroxy derivatives. SCOM are designed to be small enough to enter cells or bacteria via cell membranes or cell walls, respectively. Therefor...
متن کاملCell surface phosphatidylinositol-anchored heparan sulfate proteoglycan initiates mouse melanoma cell adhesion to a fibronectin-derived, heparin-binding synthetic peptide
Cell surface heparan sulfate proteoglycan (HSPG) from metastatic mouse melanoma cells initiates cell adhesion to the synthetic peptide FN-C/H II, a heparin-binding peptide from the 33-kD A chain-derived fragment of fibronectin. Mouse melanoma cell adhesion to FN-C/H II was sensitive to soluble heparin and pretreatment of mouse melanoma cells with heparitinase. In contrast, cell adhesion to the ...
متن کاملInhibition of cell adhesion by a synthetic polymer adsorbed to glass shown under defined hydrodynamic stress.
A co-polymer with hydrophobic and hydrophilic segments was allowed to adsorb from aqueous solution onto glass previously made hydrophobic by derivatization with octadecyl dimethylchlorosilane. The polymer is thought to adsorb via its hydrophobic segments, leaving the hydrophilic segments free to extend into the water. After allowing cells to settle on the treated surface, the shear stress at th...
متن کاملC lostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII
Gram-positive surface proteins can be covalently or non-covalently anchored to the cell wall and can impart important properties on the bacterium in respect of cell envelope organisation and interaction with the environment. We describe here a mechanism of protein anchoring involving tandem CWB2 motifs found in a large number of cell wall proteins in the Firmicutes. In the Clostridium difficile...
متن کاملSynthetic mimics of small Mammalian cell surface receptors.
Receptors on the surface of mammalian cells promote the uptake of cell-impermeable ligands by receptor-mediated endocytosis. To mimic this process, we synthesized small molecules designed to project anti-dinitrophenyl antibody-binding motifs from the surface of living Jurkat lymphocytes. These synthetic receptors comprise N-alkyl derivatives of 3beta-cholesterylamine as the plasma membrane anch...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Soft Matter
سال: 2015
ISSN: 1744-683X,1744-6848
DOI: 10.1039/c5sm90037a